Monday, August 30, 2021

Research finds ‘very low rates’ of dental fluoride varnish treatment for young children

 Affordable Care Act mandates insurance coverage for the service during well-child visits to medical provider

 Fewer than 5% of well-child visits for privately insured young children included a recommended dental fluoride varnish application, despite mandatory insurance coverage for this service, according to a University of Massachusetts Amherst study.

Fluoride varnish helps reduce tooth decay, which affects nearly 25% of 2- to 5-year-olds and more than half of 6- to 8-year-olds in the U.S., according to earlier studies. 

The new research, published Aug. 30 in JAMA Network Open, was the first to assess delivery of this evidence-based service recommended by the U.S. Preventive Task Force and the American Academy of Pediatrics for privately insured children. Previous research showed that fewer than 8% of 1- to 5-year-olds covered by Medicaid receive fluoride varnish in medical settings. 

While Medicaid in most states has paid for fluoride varnish applications for at least a decade, private insurance coverage was mandated in 2015 under the Affordable Care Act with no cost-share for families, explains lead author Kimberley Geissler, associate professor of health policy and management in the UMass Amherst School of Public Health and Health Sciences.

“Most kids are not getting fluoride varnish applications in the medical office,” Geissler says. “I wasn’t surprised due to the low rates we’ve seen in Medicaid-covered children, but I was disappointed that it wasn’t higher. Medical providers are not required to do this; it’s like a mammogram. It’s recommended and it’s good and they should do it, and the questions we were looking at were: do they do it and how often?”

Co-author and pediatrician Dr. Sarah Goff, associate professor of health policy and management at UMass Amherst, saysknowing that very low rates of fluoride varnish application are found in both Medicaid and commercially insured populations is important because it suggests that broader, system-level barriers exist. “As a health services researcher and primary care pediatrician, I am excited about our next steps of learning what sorts of things are presenting barriers to applying fluoride varnish and developing strategies for overcoming these barriers so all eligible children receive this important preventive intervention,” Goff says.

The JAMA study is part of a larger project in Massachusetts that will delve into more complex questions, such as whymedical providers aren’t applying fluoride varnish during well-child visits. The preventive treatment is especially critical in light of the statistic that fewer than one in three children under age 5 have an annual dentist visit, where this service also could be provided.

The research team, including senior author Ashley Kranz of the RAND Corporation, examined data from 2016-2018 for privately insured young children in Connecticut, Maine, New Hampshire and Rhode Island.

The sample included 328,661 well-child visits in the four states. Fluoride varnish application was more common among visits for younger children. A 2-year-old was nearly 8 percentage points more likely to receive fluoride varnish than a 5-year-old, an analysis of the data showed.

Fluoride varnish applications were most common in Rhode Island, with a regression-adjusted probability of 8.7%. New Hampshire had the lowest rate, with a regression-adjusted probability of 2.2%.

Geissler points to one “hopeful takeaway” from the study: the regression-adjusted probability of fluoride varnish application increased from 3.6% in 2016 to 5.8% in 2018. “That’s still really low,” she says, “but it did go up over time.”

The study concludes, “Although increases over time were encouraging, very low rates of fluoride varnish in medical settings suggest substantial expansion of this service in medical settings is critical for improving children’s oral health and overall well-being.” 


Wednesday, August 25, 2021

Gum disease linked with new onset heart disease

 

Reports and Proceedings

EUROPEAN SOCIETY OF CARDIOLOGY

Sophia Antipolis, France – 25 Aug 2021:  Gum disease is associated with an increased risk of cardiovascular disease: the more severe the periodontitis, the higher the risk. The findings are presented at ESC Congress 2021.1 The association was particularly evident among patients who had experienced a heart attack in the past.

Study author Dr. Giulia Ferrannini of the Karolinska Institute, Stockholm, Sweden said: “Our study suggests that dental screening programmes including regular check-ups and education on proper dental hygiene may help to prevent first and subsequent heart events.”

The Swedish PAROKRANK study previously showed that periodontitis (gum disease) was significantly more common in first time heart attack patients compared to their healthy peers of the same age and sex and living in the same area.2

This long-term follow-up of PAROKRANK participants investigated whether the presence of gum disease, both in heart attack patients and their healthy peers, was related to an increased risk of new cardiovascular events over time.

The analysis included 1,587 participants with an average age of 62 years. Participants underwent a dental examination between 2010 and 2014: 985 were classified as healthy, 489 had moderate periodontitis, and 113 had severe periodontitis. Participants were followed up for the occurrence of cardiovascular events and death. The primary endpoint was a composite of all-cause death, non-fatal heart attack or stroke, or severe heart failure. Follow-up data were collected until the end of 2018 from Swedish national death and patient registries.

During an average follow up of 6.2 years, there were 205 primary endpoint events. In the overall cohort, participants with periodontitis at baseline had 49% higher odds of the primary endpoint compared to those with healthy gums. The probability of the primary endpoint rose with increasing severity of gum disease.

When heart attack patients and healthy controls were assessed separately, the graded relationship between gum disease severity and the primary endpoint was significant only for patients.

Dr. Ferrannini said: “The risk of experiencing a cardiovascular event during follow-up was higher in participants with periodontitis, increasing in parallel with the severity. This was particularly apparent in patients who had already experienced a myocardial infarction.”

She added: “We postulate that the damage of periodontal tissues in people with gum disease may facilitate the transfer of germs into the bloodstream. This could accelerate harmful changes to the blood vessels and/or enhance systemic inflammation that is harmful to the vessels.”

Dr. Ferrannini concluded: “It is important to underline that the quality of care in Sweden is high, as confirmed by the overall low number of total events during follow-up. Despite this, gum disease was linked with an elevated likelihood of cardiovascular disease or death.”


Tuesday, August 3, 2021

Dental mitigation strategies to reduce aerosolization of SARS-CoV-2


Peer-Reviewed Publication

INTERNATIONAL & AMERICAN ASSOCIATIONS FOR DENTAL RESEARCH

Alexandria, Va., USA — Limiting infection transmission is central to the safety of all in dentistry, particularly during the current SARS-CoV-2 pandemic, yet many dental procedures unavoidably generate aerosols. In the study “Dental Mitigation Strategies to Reduce Aerosolization of SARS-CoV-2,” published in the Journal of Dental Research (JDR), researchers at the University of Leeds, England, UK used a ‘phantom head’ model to mimic dental procedures in a multifaceted approach to measure aerosol dispersal in a dental surgery setting and determine the potential of different mitigation strategies to reduce the infection risk to the dental team from bioaerosol exposure during routine dental procedures.

In a dental surgery setting, crown preparation and root canal access procedures were performed with an air turbine or high-speed contra-angle hand-piece (HSCAH) operated with water cooling, with mitigation via rubber dam or high-volume aspiration and a no mitigation control. A phantom head was used with a flow of artificial saliva infected with Φ6-bacteriophage, a surrogate virus for SARS-CoV-2. Bioaerosol dispersal was measured using agar settle plates lawned with the Φ6-bacteriophage host, Pseudomonas syringae. Viral air concentrations were assessed by active air sampling, and particle size and quantities were monitored using optical particle counters.

Bioaerosol levels were clearly diminished when using the HSCAH compared with the air turbine. Use of rubber dam or high volume evacuation were also effective in reducing bioaerosols and splatter.

While this model represents a worst-case scenario for possible SARS-CoV-2 dispersal, these data showed that the use of HSCAHs or other mitigation strategies can vastly reduce the risk of viral aerosolization, and suggests a prolonged clinic fallow time is not necessary.

“It is imperative to understand the inherent risks of viral dispersion associated with dental procedures and the efficacy of available mitigation strategies,” said JDR Editor-in-Chief Nicholas Jakubovics, Newcastle University, England. “To our knowledge, this study is the first to report the aerosolization in a simulated dental setting of bacteriophage, as a surrogate for SARS CoV2, as a marker for risk determination. The data described here present a clear picture of how risk of SARS-CoV-2 and similar biological hazards can be greatly attenuated using mitigation strategies including HSCAHs.”

Reducing COVID-19 risk during dentist appointments

Dentists could significantly increase the number of patients they see during the pandemic by switching the drills they use, according to new research. 

The study investigated whether different drill types increased or reduced the spread of aerosol spray in a dental surgery. Reducing aerosol spray results in a safer environment for patients and the dental team. 

The findings show that the time taken to prepare safe surgeries between appointments could be radically reduced by changing drills, potentially resulting in millions more treatments being carried out. 

The study, led by the University of Leeds, compared the aerosol patterns produced by dental drills rotated by air streams - that are most commonly used by UK dentists - to those produced by electric powered drills. 

Instead of simply mapping the spread of water spray during treatment, the research team instead introduced a virus that is similar in size and structure to the SARS-CoV-2 virus that causes COVID-19. 

Their results show that by replacing the high-speed air drills with lower speed electric drills, aerosol spray was virtually eliminated, creating a safer environment for both patients and the dental team. 

The research, funded by the British Endodontic Society, is published in the Journal of Dental Research. 

Lead clinical author Professor Brian Nattress, from Leeds’ School of Dentistry, said: “The issue for dentists during the coronavirus pandemic is that their routine work involves creating an aerosol spray in a confined space with an associated risk of airborne spread of COVID-19. 

“This is the first time the spread of a harmless COVID-19-like virus has been analysed during routine drilling procedures. 

“If the spread of that aerosol spray can be reduced or eradicated, that has enormous, positive implications for how dentists can go about their daily business not just during the coronavirus pandemic, but also during future virus outbreaks.” 

During the first national lockdown in England between March and June 2020, all dental surgeries were closed. 

Since reopening, because patients may be asymptomatic carriers of the SARS-CoV-2 virus when attending a dentist appointment, strict regulations have been introduced to ensure work areas are safe and prepared appropriately between appointments. Additional protective measures have been required for the dental team delivering patient care. This has led to much longer gaps between treating patients.  

Before the pandemic, about 18 million adults and children attended an NHS dental appointment each year in England. 

Reports by charity HealthWatch point to a growing backlog of patients waiting to see a dentist, with fears this could rise as the SARS-CoV-2 virus is expected to remain prevalent in the general population for many months more. 

Adjustments to the pandemic measures require high quality evidence to show how dentists can reduce the risk of spreading the SARS-CoV-2 virus when carrying out aerosol generating procedures (AGPs) during dental treatments. 

During the new research tests, use of the electric drill rather than an air drill led to a 99.98% reduction in aerosol spread of the virus into the air. 

When a dental suction tool was added, there was no detectable virus on surfaces or in air samples taken six to 10 minutes afterwards. 

The new research was carried out by the School of Dentistry, School of Civil Engineering and the Leeds Dental Institute. 

The research team set up simulated dental treatments in a real surgery scenario and - for the first time ever - used a harmless virus to track the spread of aerosols in the air and on surfaces. 

A dummy head and simulated saliva were used to measure the difference between the level of aerosols generated using a conventional air-driven dentist’s drill and a more modern electric hand piece. 

Professor David Wood, Director of Research and Innovation in the School of Dentistry, is co-author of the report. 

He said: “This robust scientific evidence addresses how the risks associated with the spread of the SARS-CoV-2 virus via dental drills can be successfully managed. 

“The recommendation we make in the report will help more people access the dental care they need, but haven’t been able to get since early 2020.” 

In light of the many restraints placed on dentists globally since the beginning of the pandemic, the research team is calling for further and essential studies to find different strategies to control the spread of dental aerosols and help to reduce the backlog of patients. 

Further information 

“Dental mitigation strategies to reduce aerosolization 1 of SARS-CoV-2”, is published on 2 August 2021 in the Journal of Dental Research. 

DOI: https://doi.org/10.1177/00220345211032885